Maha Sarakham Province is one of the 76 provinces (changwat) of Thailand. It is in the northeastern (Isan) region of Thailand. Neighbouring provinces are (from north clockwise): Kalasin, Roi Et, Surin, Buriram, and Khon Kaen.
The town of Maha Sarakham is the provincial capital. It is the home of Mahasarakham University, the largest university in northeast Thailand with about 40,000 students, and Rajabhat Mahasarakham University.